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Mathematical modeling on bacterial resistance to multiple antibiotics caused by spontaneous mutations

Ibargüen-Mondragón, Eduardo Y Mosquera-López, Saulo Y Cerón G., Miller Y Burbano-Rosero, Edith Y Hidalgo-Bonilla, Sandra Y Esteva P., Lourdes Y Romero, Jhoana P. (2014) Mathematical modeling on bacterial resistance to multiple antibiotics caused by spontaneous mutations. Biosystems, 117. pp. 60-67. ISSN 0303-2647

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URL Oficial: http://dx.doi.org/10.1016/j.biosystems.2014.01.005

Resumen

We formulate a mathematical model that describes the population dynamics of bacteria exposed to multiple antibiotics simultaneously, assuming that acquisition of resistance is through mutations due to antibiotic exposure. Qualitative analysis reveals the existence of a free-bacteria equilibrium, resistant-bacteria equilibrium and an endemic equilibrium where both bacteria coexist.

Tipo de Elemento: Artículo
Palabras Clave: Ordinary differential equations; Equilibrium solutions; Bacterial resistance; Antibiotics
Asunto: Q Ciencias > QA Mathematics
Division: Facultad de Ciencias Exactas y Naturales > Programa de Licenciatura en Matemáticas > Productividad
Depósito de Usuario: Dr. Eduardo Ibarguen Mondragon
Fecha Deposito: 02 Mar 2017 22:33
Ultima Modificación: 02 Mar 2017 22:33
URI: http://sired.udenar.edu.co/id/eprint/3791

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